Desmopressin and bleeding time in patients with cirrhosis.

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Bleeding time in patients with hepatic cirrhosis.

OBJECTIVE To determine the frequency of an abnormal bleeding time in patients with cirrhosis and to relate this to known factors that affect primary haemostasis and to the severity of liver disease. DESIGN Prospective clinical and laboratory study in patients admitted for complications or investigations of liver disease. SETTING Royal Free Hospital hepatobiliary and liver transplantation un...

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Controlled trial of desmopressin in liver cirrhosis and other conditions associated with a prolonged bleeding time.

The synthetic vasopressin derivative desmopressin (DDAVP) shortens a prolonged bleeding time (BT) in patients with uremia, congenital platelet dysfunction, and von Willebrand disease. To establish the limits of the clinical usefulness of DDAVP, a controlled randomized study was carried out in 53 patients and ten volunteers with different conditions that have in common a prolonged BT. DDAVP sign...

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Lower gastrointestinal bleeding in patients with cirrhosis.

Lower gastrointestinal bleeding (LGIB) in patients with cirrhosis may be associated with life-threatening complications similar to upper GI bleeding (UGIB). The data on LGIB in patients with cirrhosis is surprisingly small. The true incidence, diagnoses, risks of bleeding and results of treatment remain poorly defined, since there are no large epidemiologic studies available. Much of the data a...

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Bleeding complications in critically ill patients with liver cirrhosis

BACKGROUND/AIMS Patients with liver cirrhosis (LC) are at risk for critical events leading to Intensive Care Unit (ICU) admission. Coagulopathy in cirrhotic patients is complex and can lead to bleeding as well as thrombosis. The aim of this study was to investigate bleeding complications in critically ill patients with LC admitted to a medical ICU (MICU). METHODS All adult patients admitted t...

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ژورنال

عنوان ژورنال: BMJ

سال: 1986

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.292.6513.138-a